miR-148b-3p functions as a tumor suppressor in GISTs by directly targeting KIT

BACKGROUND: Gain-of-function mutations and overexpression of KIT are characteristic features of gastrointestinal stromal tumor (GIST). Dysregulation in miRNA expression may lead to KIT overexpression and tumorigenesis. METHODS: miRNA microarray analysis and real-time PCR were used to determine the m...

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Detalles Bibliográficos
Autores principales: Wang, Yu, Li, Jun, Kuang, Dong, Wang, Xiaoyan, Zhu, Yuanli, Xu, Sanpeng, Chen, Yaobing, Cheng, Henghui, Zhao, Qiu, Duan, Yaqi, Wang, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902930/
https://www.ncbi.nlm.nih.gov/pubmed/29661252
http://dx.doi.org/10.1186/s12964-018-0228-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902930/
https://www.ncbi.nlm.nih.gov/pubmed/29661252
http://dx.doi.org/10.1186/s12964-018-0228-z

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