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miR-148b-3p functions as a tumor suppressor in GISTs by directly targeting KIT

BACKGROUND: Gain-of-function mutations and overexpression of KIT are characteristic features of gastrointestinal stromal tumor (GIST). Dysregulation in miRNA expression may lead to KIT overexpression and tumorigenesis. METHODS: miRNA microarray analysis and real-time PCR were used to determine the m...

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Detalles Bibliográficos
Autores principales:	Wang, Yu, Li, Jun, Kuang, Dong, Wang, Xiaoyan, Zhu, Yuanli, Xu, Sanpeng, Chen, Yaobing, Cheng, Henghui, Zhao, Qiu, Duan, Yaqi, Wang, Guoping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902930/ https://www.ncbi.nlm.nih.gov/pubmed/29661252 http://dx.doi.org/10.1186/s12964-018-0228-z

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