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Energy restriction, exercise and atorvastatin treatment improve endothelial dysfunction and inhibit miRNA-155 in the erectile tissue of the aged rat.

BACKGROUND: Endothelial dysfunction underlies cardiovascular disease that frequently affects aged individuals. Characterized by local decrease in nitric oxide, it results from down-regulation of endothelial nitric oxide synthase (eNOS) expression/activity. Aiming to elucidate the molecular mechanism...

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Detalles Bibliográficos
Autores principales: Rocha, B., Rodrigues, A. R., Tomada, I., Martins, M. J., Guimarães, J. T., Gouveia, A. M., Almeida, H., Neves, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902942/
https://www.ncbi.nlm.nih.gov/pubmed/29686722
http://dx.doi.org/10.1186/s12986-018-0265-z