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Energy restriction, exercise and atorvastatin treatment improve endothelial dysfunction and inhibit miRNA-155 in the erectile tissue of the aged rat.
BACKGROUND: Endothelial dysfunction underlies cardiovascular disease that frequently affects aged individuals. Characterized by local decrease in nitric oxide, it results from down-regulation of endothelial nitric oxide synthase (eNOS) expression/activity. Aiming to elucidate the molecular mechanism...
Autores principales: | Rocha, B., Rodrigues, A. R., Tomada, I., Martins, M. J., Guimarães, J. T., Gouveia, A. M., Almeida, H., Neves, D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902942/ https://www.ncbi.nlm.nih.gov/pubmed/29686722 http://dx.doi.org/10.1186/s12986-018-0265-z |
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