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Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa

BACKGROUND: Retinitis pigmentosa (RP) is a group of hereditary retinal neurodegenerative conditions characterized by primary dysfunction and death of photoreceptor cells, resulting in visual loss and, eventually, blindness. To date, no effective therapies have been transferred to clinic. Given the d...

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Detalles Bibliográficos
Autores principales: Sánchez-Cruz, Alonso, Villarejo-Zori, Beatriz, Marchena, Miguel, Zaldivar-Díez, Josefa, Palomo, Valle, Gil, Carmen, Lizasoain, Ignacio, de la Villa, Pedro, Martínez, Ana, de la Rosa, Enrique J., Hernández-Sánchez, Catalina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902946/
https://www.ncbi.nlm.nih.gov/pubmed/29661219
http://dx.doi.org/10.1186/s13024-018-0251-y