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Modulation of GSK-3 provides cellular and functional neuroprotection in the rd10 mouse model of retinitis pigmentosa
BACKGROUND: Retinitis pigmentosa (RP) is a group of hereditary retinal neurodegenerative conditions characterized by primary dysfunction and death of photoreceptor cells, resulting in visual loss and, eventually, blindness. To date, no effective therapies have been transferred to clinic. Given the d...
Autores principales: | Sánchez-Cruz, Alonso, Villarejo-Zori, Beatriz, Marchena, Miguel, Zaldivar-Díez, Josefa, Palomo, Valle, Gil, Carmen, Lizasoain, Ignacio, de la Villa, Pedro, Martínez, Ana, de la Rosa, Enrique J., Hernández-Sánchez, Catalina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902946/ https://www.ncbi.nlm.nih.gov/pubmed/29661219 http://dx.doi.org/10.1186/s13024-018-0251-y |
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