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Cytomegalovirus-Specific CD8+ T-Cells With Different T-Cell Receptor Affinities Segregate T-Cell Phenotypes and Correlate With Chronic Graft-Versus-Host Disease in Patients Post-Hematopoietic Stem Cell Transplantation

Virus-specific T-cell responses are crucial to control cytomegalovirus (CMV) infections/reactivation in immunocompromised individuals. Adoptive cellular therapy with CMV-specific T-cells has become a viable treatment option. High-affinity anti-viral cellular immune responses are associated with impr...

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Detalles Bibliográficos
Autores principales: Poiret, Thomas, Axelsson-Robertson, Rebecca, Remberger, Mats, Luo, Xiao-Hua, Rao, Martin, Nagchowdhury, Anurupa, Von Landenberg, Anna, Ernberg, Ingemar, Ringden, Olle, Maeurer, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903031/
https://www.ncbi.nlm.nih.gov/pubmed/29692783
http://dx.doi.org/10.3389/fimmu.2018.00760