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MicroRNA-22 Promotes Renal Tubulointerstitial Fibrosis by Targeting PTEN and Suppressing Autophagy in Diabetic Nephropathy

Renal tubulointerstitial fibrosis (TIF) is a major feature of diabetic nephropathy (DN). There is increasing evidence demonstrating that microRNAs act as key players in the regulation of autophagy and are involved in DN. However, the exact link among microRNAs, autophagy, and TIF in DN is largely un...

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Detalles Bibliográficos
Autores principales: Zhang, Yingying, Zhao, Siqi, Wu, Depei, Liu, Xingmei, Shi, Mingjun, Wang, Yuanyuan, Zhang, Fan, Ding, Jing, Xiao, Ying, Guo, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903315/
https://www.ncbi.nlm.nih.gov/pubmed/29850604
http://dx.doi.org/10.1155/2018/4728645