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Role of Atp7b Gene in Spontaneous and N‐Diethylnitrosamine‐induced Carcinogenesis in a New Congenic Strain, WKAH.C‐Atp7b Rats

To examine whether Long‐Evans Cinnamon (LEC) rats, a mutant rat model of Wilson's disease, have a susceptibility gene(s) to hepatocarcinogenesis in addition to the causative gene, Atp7b, we established a new congenic strain, WKAH.C‐Atp7b rats, in which the Atp7b gene of the LEG rats is inserted...

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Detalles Bibliográficos
Autores principales: Minami, Takanori, Kaneda, Shinya, Otsuka, Toshihiro, Jiao, Zhongxian, Suzuki, Yasuo, Yamada, Takahisa, Matsumoto, Kozo, Izumi, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903424/
https://www.ncbi.nlm.nih.gov/pubmed/11509115
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01170.x