A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma

The heterogeneity of cellular states in cancer has been linked to drug resistance, cancer progression and presence of cancer cells with properties of normal tissue stem cells(1,2). Secreted Wnt signals maintain stem cells in various epithelial tissues, including in lung development and regeneration(...

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Detalles Bibliográficos
Autores principales: Tammela, Tuomas, Sanchez-Rivera, Francisco J., Cetinbas, Naniye Malli, Wu, Katherine, Joshi, Nikhil S., Helenius, Katja, Park, Yoona, Azimi, Roxana, Kerper, Natanya R., Wesselhoeft, R. Alexander, Gu, Xin, Schmidt, Leah, Cornwall-Brady, Milton, Yilmaz, Ömer H., Xue, Wen, Katajisto, Pekka, Bhutkar, Arjun, Jacks, Tyler
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903678/
https://www.ncbi.nlm.nih.gov/pubmed/28489818
http://dx.doi.org/10.1038/nature22334

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903678/
https://www.ncbi.nlm.nih.gov/pubmed/28489818
http://dx.doi.org/10.1038/nature22334

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