Cargando…

PI3Kδ contributes to ER stress-associated asthma through ER-redox disturbances: the involvement of the RIDD–RIG-I–NF-κB axis

Hyperactivation of phosphoinositol 3-kinase (PI3K) has been suggested to be a potential mechanism for endoplasmic reticulum (ER) stress-enhanced airway hyperresponsiveness, and PI3K inhibitors have been examined as asthma therapeutics. However, the regulatory mechanism linking PI3K to ER stress and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Hyun-Kyoung, Lee, Geum-Hwa, Bhattarai, Kashi Raj, Junjappa, Raghu Patil, Lee, Hwa-Young, Handigund, Mallikarjun, Marahatta, Anu, Bhandary, Bidur, Baek, In-Hwan, Pyo, Jae Sung, Kim, Hye-Kyung, Chai, Ok Hee, Kim, Hyung-Ryong, Lee, Yong-Chul, Chae, Han-Jung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903822/ https://www.ncbi.nlm.nih.gov/pubmed/29504610 http://dx.doi.org/10.1038/emm.2017.270

Ejemplares similares

Characterization of Salvia Miltiorrhiza ethanol extract as an anti-osteoporotic agent
por: Cui, Yan, et al.
Publicado: (2011)

Role of Endoplasmic Reticulum Stress Sensor IRE1α in Cellular Physiology, Calcium, ROS Signaling, and Metaflammation
por: Riaz, Thoufiqul Alam, et al.
Publicado: (2020)

An Involvement of Oxidative Stress in Endoplasmic Reticulum Stress and Its Associated Diseases
por: Bhandary, Bidur, et al.
Publicado: (2012)

Polyphenolic Extract of Euphorbia supina Attenuates Manganese-Induced Neurotoxicity by Enhancing Antioxidant Activity through Regulation of ER Stress and ER Stress-Mediated Apoptosis
por: Bahar, Entaz, et al.
Publicado: (2017)

Soybean greatly reduces valproic acid plasma concentrations: A food–drug interaction study
por: Marahatta, Anu, et al.
Publicado: (2014)

Protective role of quercetin against manganese-induced injury in the liver, kidney, and lung; and hematological parameters in acute and subchronic rat models
por: Bahar, Entaz, et al.
Publicado: (2017)

Chalcone suppresses tumor growth through NOX4-IRE1α sulfonation-RIDD-miR-23b axis
por: Kim, Hyun-Kyoung, et al.
Publicado: (2021)

IRE1α Implications in Endoplasmic Reticulum Stress-Mediated Development and Pathogenesis of Autoimmune Diseases
por: Junjappa, Raghu Patil, et al.
Publicado: (2018)

Eucommia ulmoides Oliver Extract, Aucubin, and Geniposide Enhance Lysosomal Activity to Regulate ER Stress and Hepatic Lipid Accumulation
por: Lee, Hwa-Young, et al.
Publicado: (2013)

Apoptosis Induced by Manganese on Neuronal SK-N-MC Cell Line: Endoplasmic Reticulum (ER) Stress and Mitochondria Dysfunction
por: Yoon, Hyonok, et al.
Publicado: (2011)

Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress
por: Lee, Hwa-Young, et al.
Publicado: (2017)

GABA and Fermented Curcuma longa L. Extract Enriched with GABA Ameliorate Obesity through Nox4-IRE1α Sulfonation-RIDD-SIRT1 Decay Axis in High-Fat Diet-Induced Obese Mice
por: Lee, Hwa-Young, et al.
Publicado: (2022)

Can’t RIDD off viruses
por: Bhattacharyya, Sankar
Publicado: (2014)

Phosphatidylinositol 3‐kinase‐δ controls endoplasmic reticulum membrane fluidity and permeability in fungus‐induced allergic inflammation in mice
por: Lee, Hwa‐Young, et al.
Publicado: (2020)

Expression of TMBIM6 in Cancers: The Involvement of Sp1 and PKC
por: Junjappa, Raghu Patil, et al.
Publicado: (2019)

Bax Inhibitor-1 regulates hepatic lipid accumulation via ApoB secretion
por: Lee, Hwa Young, et al.
Publicado: (2016)

TMBIM6 regulates redox-associated posttranslational modifications of IRE1α and ER stress response failure in aging mice and humans
por: Bhattarai, Kashi Raj, et al.
Publicado: (2021)

TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium
por: Kim, Hyun-Kyoung, et al.
Publicado: (2020)

TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation
por: Kim, Hyun-Kyoung, et al.
Publicado: (2020)

IBF-R Regulates IRE1α Post-Translational Modifications and ER Stress in High-Fat Diet-Induced Obese Mice
por: Lee, Hwa-Young, et al.
Publicado: (2022)

Ixeris dentata Extract Increases Salivary Secretion through the Regulation of Endoplasmic Reticulum Stress in a Diabetes-Induced Xerostomia Rat Model
por: Bhattarai, Kashi Raj, et al.
Publicado: (2018)

Effect of a Er, Cr:YSGG laser and a Er:YAG laser treatment on oral biofilm-contaminated titanium
por: Park, So-Hyun, et al.
Publicado: (2020)

Potential Application of Ixeris dentata in the Prevention and Treatment of Aging-Induced Dry Mouth
por: Bhattarai, Kashi Raj, et al.
Publicado: (2018)

Porcine placenta hydrolysates enhance osteoblast differentiation through their antioxidant activity and effects on ER stress
por: Lee, Hwa-Young, et al.
Publicado: (2016)

3,3′-Diindolylmethane Suppresses the Growth of Hepatocellular Carcinoma by Regulating Its Invasion, Migration, and ER Stress-Mediated Mitochondrial Apoptosis
por: Munakarmi, Suvesh, et al.
Publicado: (2021)

Calreticulin modulates the intracellular survival of mycobacteria by regulating ER-stress-mediated apoptosis
por: Jo, Sung Hee, et al.
Publicado: (2017)

The protective role of Bax Inhibitor-1 against chronic mild stress through the inhibition of monoamine oxidase A
por: Lee, Hwa-Young, et al.
Publicado: (2013)

IRE1α RIDD activity induced under ER stress drives neuronal death by the degradation of 14-3-3 θ mRNA in cortical neurons during glucose deprivation
por: Gómora-García, Juan Carlos, et al.
Publicado: (2021)

Metformin ameliorates bile duct ligation-induced acute hepatic injury via regulation of ER stress
por: Lee, Chi-Ho, et al.
Publicado: (2020)

Brucella activates the host RIDD pathway to subvert BLOS1-directed immune defense
por: Wells, Kelsey Michelle, et al.
Publicado: (2022)

Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting Endoplasmic Reticulum (ER) Stress Induced by Disturbed Flow
por: Chung, Jihwa, et al.
Publicado: (2015)

Profiling of the Mammalian Mitotic Spindle Proteome Reveals an ER Protein, OSTD-1, as Being Necessary for Cell Division and ER Morphology
por: Bonner, Mary Kate, et al.
Publicado: (2013)

Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells
por: Lim, Yun, et al.
Publicado: (2021)

Taurine reduces ER stress in C. elegans
por: Kim, Hye Min, et al.
Publicado: (2010)

BI-1 enhances Fas-induced cell death through a Na(+)/H(+)-associated mechanism
por: Lee, Geum-Hwa, et al.
Publicado: (2014)

Functions and physiological roles of two types of estrogen receptors, ERα and ERβ, identified by estrogen receptor knockout mouse
por: Lee, Hye-Rim, et al.
Publicado: (2012)

Bax Inhibitor-1-Mediated Inhibition of Mitochondrial Ca(2+) Intake Regulates Mitochondrial Permeability Transition Pore Opening and Cell Death
por: Lee, Geum-Hwa, et al.
Publicado: (2014)

Correction: Profiling of the Mammalian Mitotic Spindle Proteome Reveals an ER Protein, OSTD-1, as Being Necessary for Cell Division and ER Morphology
por: Bonner, Mary Kate, et al.
Publicado: (2017)

Evaluation of Er Doped CeO(2-δ) as Oxygen Transport Membrane
por: Balaguer, María, et al.
Publicado: (2022)

Clinical Features and Risk Factors Associated With 30-Day Mortality in Patients With Pneumonia Caused by Hypervirulent Klebsiella pneumoniae (hvKP)
por: Hwang, Jeong-Hwan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_oansv1jv78mphhp3j2mm6r62s8