Suppression of the ERK–SRF axis facilitates somatic cell reprogramming

The molecular mechanism underlying the initiation of somatic cell reprogramming into induced pluripotent stem cells (iPSCs) has not been well described. Thus, we generated single-cell-derived clones by using a combination of drug-inducible vectors encoding transcription factors (Oct4, Sox2, Klf4 and...

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Detalles Bibliográficos
Autores principales: Huh, Sejong, Song, Hwa-Ryung, Jeong, Geuk-Rae, Jang, Hyejin, Seo, Nan-Hee, Lee, Ju-Hyun, Yi, Ji-Yeun, Lee, Byongsun, Choi, Hyun Woo, Do, Jeong Tae, Kim, Jin-Su, Lee, Soo-Hong, Jung, Jae-Won, Lee, Taekyu, Shim, Jaekyung, Han, Myung-Kwan, Lee, Tae-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903827/
https://www.ncbi.nlm.nih.gov/pubmed/29472703
http://dx.doi.org/10.1038/emm.2017.279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903827/
https://www.ncbi.nlm.nih.gov/pubmed/29472703
http://dx.doi.org/10.1038/emm.2017.279

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