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MicroRNA-142-3p is involved in regulation of MGMT expression in glioblastoma cells

BACKGROUND: Glioblastoma multiforme (GBM) is the most malignant brain tumor, and there is no effective treatment strategy. Patients with GBM have a median overall survival of only 14.6 months. Current treatment consists of safe and maximal surgical excision, followed by concurrent chemoradiotherapy...

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Detalles Bibliográficos
Autores principales: Lee, Yi-Yen, Yarmishyn, Aliaksandr A, Wang, Mong-Lien, Chen, Hsiao-Yun, Chiou, Shih-Hwa, Yang, Yi-Ping, Lin, Chun-Fu, Huang, Pin-I, Chen, Yi-Wei, Ma, Hsin-I, Chen, Ming-Teh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903834/
https://www.ncbi.nlm.nih.gov/pubmed/29695934
http://dx.doi.org/10.2147/CMAR.S157261