Acyl chain asymmetry and polyunsaturation of brain phospholipids facilitate membrane vesiculation without leakage

Phospholipid membranes form cellular barriers but need to be flexible enough to divide by fission. Phospholipids generally contain a saturated fatty acid (FA) at position sn1 whereas the sn2-FA is saturated, monounsaturated or polyunsaturated. Our understanding of the impact of phospholipid unsatura...

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Detalles Bibliográficos
Autores principales: Manni, Marco M, Tiberti, Marion L, Pagnotta, Sophie, Barelli, Hélène, Gautier, Romain, Antonny, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903860/
https://www.ncbi.nlm.nih.gov/pubmed/29543154
http://dx.doi.org/10.7554/eLife.34394

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903860/
https://www.ncbi.nlm.nih.gov/pubmed/29543154
http://dx.doi.org/10.7554/eLife.34394

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