An incoherent feedforward loop facilitates adaptive tuning of gene expression

We studied adaptive evolution of gene expression using long-term experimental evolution of Saccharomyces cerevisiae in ammonium-limited chemostats. We found repeated selection for non-synonymous variation in the DNA binding domain of the transcriptional activator, GAT1, which functions with the repr...

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Detalles Bibliográficos
Autores principales: Hong, Jungeui, Brandt, Nathan, Abdul-Rahman, Farah, Yang, Ally, Hughes, Tim, Gresham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903863/
https://www.ncbi.nlm.nih.gov/pubmed/29620523
http://dx.doi.org/10.7554/eLife.32323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903863/
https://www.ncbi.nlm.nih.gov/pubmed/29620523
http://dx.doi.org/10.7554/eLife.32323

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