Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility

The inwardly rectifying K(+) channel K(ir)4.1 is broadly expressed by CNS glia and deficits in K(ir)4.1 lead to seizures and myelin vacuolization. However, the role of oligodendrocyte K(ir)4.1 channels in controlling myelination and K(+) clearance in white matter has not been defined. Here, we show...

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Detalles Bibliográficos
Autores principales: Larson, Valerie A, Mironova, Yevgeniya, Vanderpool, Kimberly G, Waisman, Ari, Rash, John E, Agarwal, Amit, Bergles, Dwight E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903864/
https://www.ncbi.nlm.nih.gov/pubmed/29596047
http://dx.doi.org/10.7554/eLife.34829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903864/
https://www.ncbi.nlm.nih.gov/pubmed/29596047
http://dx.doi.org/10.7554/eLife.34829

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