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Oligodendrocytes control potassium accumulation in white matter and seizure susceptibility
The inwardly rectifying K(+) channel K(ir)4.1 is broadly expressed by CNS glia and deficits in K(ir)4.1 lead to seizures and myelin vacuolization. However, the role of oligodendrocyte K(ir)4.1 channels in controlling myelination and K(+) clearance in white matter has not been defined. Here, we show...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903864/ https://www.ncbi.nlm.nih.gov/pubmed/29596047 http://dx.doi.org/10.7554/eLife.34829 |