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Bioengineered Systems and Designer Matrices That Recapitulate the Intestinal Stem Cell Niche
The relationship between intestinal stem cells (ISCs) and the surrounding niche environment is complex and dynamic. Key factors localized at the base of the crypt are necessary to promote ISC self-renewal and proliferation, to ultimately provide a constant stream of differentiated cells to maintain...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904029/ https://www.ncbi.nlm.nih.gov/pubmed/29675459 http://dx.doi.org/10.1016/j.jcmgh.2018.01.008 |