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Bioengineered Systems and Designer Matrices That Recapitulate the Intestinal Stem Cell Niche

The relationship between intestinal stem cells (ISCs) and the surrounding niche environment is complex and dynamic. Key factors localized at the base of the crypt are necessary to promote ISC self-renewal and proliferation, to ultimately provide a constant stream of differentiated cells to maintain...

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Detalles Bibliográficos
Autores principales: Wang, Yuli, Kim, Raehyun, Hinman, Samuel S., Zwarycz, Bailey, Magness, Scott T., Allbritton, Nancy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904029/
https://www.ncbi.nlm.nih.gov/pubmed/29675459
http://dx.doi.org/10.1016/j.jcmgh.2018.01.008