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Formation of Human Colonic Crypt Array by Application of Chemical Gradients Across a Shaped Epithelial Monolayer

BACKGROUND & AIMS: The successful culture of intestinal organoids has greatly enhanced our understanding of intestinal stem cell physiology and enabled the generation of novel intestinal disease models. Although of tremendous value, intestinal organoid culture systems have not yet fully recapitu...

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Detalles Bibliográficos
Autores principales: Wang, Yuli, Kim, Raehyun, Gunasekara, Dulan B., Reed, Mark I., DiSalvo, Matthew, Nguyen, Daniel L., Bultman, Scott J., Sims, Christopher E., Magness, Scott T., Allbritton, Nancy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904049/
https://www.ncbi.nlm.nih.gov/pubmed/29693040
http://dx.doi.org/10.1016/j.jcmgh.2017.10.007