Cargando…

HATRIC-based identification of receptors for orphan ligands

Cellular responses depend on the interactions of extracellular ligands, such as nutrients, growth factors, or drugs, with specific cell-surface receptors. The sensitivity of these interactions to non-physiological conditions, however, makes them challenging to study using in vitro assays. Here we pr...

Descripción completa

Detalles Bibliográficos
Autores principales: Sobotzki, Nadine, Schafroth, Michael A., Rudnicka, Alina, Koetemann, Anika, Marty, Florian, Goetze, Sandra, Yamauchi, Yohei, Carreira, Erick M., Wollscheid, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904110/
https://www.ncbi.nlm.nih.gov/pubmed/29666374
http://dx.doi.org/10.1038/s41467-018-03936-z