Cargando…

Psoriasis patients demonstrate HLA-Cw*06:02 allele dosage-dependent T cell proliferation when treated with hair follicle-derived keratin 17 protein

It is broadly accepted that psoriasis is an immune-mediated disease with a heritable component, but it is not clear what causes inflammation in the skin. Previous research suggests that fragments of the keratin 17 (K17) protein, which are constitutively expressed in hair follicles, could act as auto...

Descripción completa

Detalles Bibliográficos
Autores principales: Yunusbaeva, Milyausha, Valiev, Ruslan, Bilalov, Fanil, Sultanova, Zilya, Sharipova, Leyla, Yunusbayev, Bayazit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904118/
https://www.ncbi.nlm.nih.gov/pubmed/29666398
http://dx.doi.org/10.1038/s41598-018-24491-z