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Signaling pathways responsible for the rapid antidepressant-like effects of a GluN2A-preferring NMDA receptor antagonist

In a previous study we found that the preferring GluN2A receptor antagonist, NVP-AAM077, elicited rapid antidepressant-like effects in the forced swim test that was related to the release of glutamate and serotonin in the medial prefrontal cortex. In the present work we sought to examine the duratio...

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Detalles Bibliográficos
Autores principales: Gordillo-Salas, Marta, Pilar-Cuéllar, Fuencisla, Auberson, Yves P., Adell, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904130/
https://www.ncbi.nlm.nih.gov/pubmed/29666360
http://dx.doi.org/10.1038/s41398-018-0131-9