Cargando…
Signaling pathways responsible for the rapid antidepressant-like effects of a GluN2A-preferring NMDA receptor antagonist
In a previous study we found that the preferring GluN2A receptor antagonist, NVP-AAM077, elicited rapid antidepressant-like effects in the forced swim test that was related to the release of glutamate and serotonin in the medial prefrontal cortex. In the present work we sought to examine the duratio...
Autores principales: | Gordillo-Salas, Marta, Pilar-Cuéllar, Fuencisla, Auberson, Yves P., Adell, Albert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904130/ https://www.ncbi.nlm.nih.gov/pubmed/29666360 http://dx.doi.org/10.1038/s41398-018-0131-9 |
Ejemplares similares
-
Allosteric modulation of GluN1/GluN3 NMDA receptors by GluN1-selective competitive antagonists
por: Rouzbeh, Nirvan, et al.
Publicado: (2023) -
Unmasking GluN1/GluN3A excitatory glycine NMDA receptors
por: Grand, Teddy, et al.
Publicado: (2018) -
GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine
por: Miller, Oliver H, et al.
Publicado: (2014) -
Uncoupling DAPK1 from NMDA receptor GluN2B subunit exerts rapid antidepressant-like effects
por: Li, S-X, et al.
Publicado: (2018) -
Subunit Arrangement and Phenylethanolamine Binding in GluN1/GluN2B NMDA Receptors
por: Karakas, Erkan, et al.
Publicado: (2011)