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Cardiac hypertrophy limits infarct expansion after myocardial infarction in mice

We have previously demonstrated that adult transgenic C57BL/6J mice with CM-restricted overexpression of the dominant negative W(v) mutant protein (dn-c-kit-Tg) respond to pressure overload with robust cardiomyocyte (CM) cell cycle entry. Here, we tested if outcomes after myocardial infarction (MI)...

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Detalles Bibliográficos
Autores principales: Iismaa, Siiri E., Li, Ming, Kesteven, Scott, Wu, Jianxin, Chan, Andrea Y., Holman, Sara R., Calvert, John W., Haq, Ahtesham ul, Nicks, Amy M., Naqvi, Nawazish, Husain, Ahsan, Feneley, Michael P., Graham, Robert M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904135/
https://www.ncbi.nlm.nih.gov/pubmed/29666426
http://dx.doi.org/10.1038/s41598-018-24525-6