Synthetic 9-cis-beta-carotene inhibits photoreceptor degeneration in cultures of eye cups from rpe65rd12 mouse model of retinoid cycle defect

The retinoid cycle enzymes regenerate the visual chromophore 11-cis retinal to enable vision. Mutations in the genes encoding the proteins of the retinoid cycle are the leading cause for recessively inherited retinal dystrophies such as retinitis pigmentosa, Leber congenital amaurosis, congenital co...

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Detalles Bibliográficos
Autores principales: Sher, Ifat, Tzameret, Adi, Peri-Chen, Sara, Edelshtain, Victoria, Ioffe, Michael, Sayer, Alon, Buzhansky, Ludmila, Gazit, Ehud, Rotenstreich, Ygal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904152/
https://www.ncbi.nlm.nih.gov/pubmed/29666392
http://dx.doi.org/10.1038/s41598-018-24439-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904152/
https://www.ncbi.nlm.nih.gov/pubmed/29666392
http://dx.doi.org/10.1038/s41598-018-24439-3

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