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Synthetic 9-cis-beta-carotene inhibits photoreceptor degeneration in cultures of eye cups from rpe65rd12 mouse model of retinoid cycle defect
The retinoid cycle enzymes regenerate the visual chromophore 11-cis retinal to enable vision. Mutations in the genes encoding the proteins of the retinoid cycle are the leading cause for recessively inherited retinal dystrophies such as retinitis pigmentosa, Leber congenital amaurosis, congenital co...
Autores principales: | Sher, Ifat, Tzameret, Adi, Peri-Chen, Sara, Edelshtain, Victoria, Ioffe, Michael, Sayer, Alon, Buzhansky, Ludmila, Gazit, Ehud, Rotenstreich, Ygal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904152/ https://www.ncbi.nlm.nih.gov/pubmed/29666392 http://dx.doi.org/10.1038/s41598-018-24439-3 |
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