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The corticosteroid compounds prednisolone and vamorolone do not alter the nociception phenotype and exacerbate liver injury in sickle cell mice

Clinicians often hesitate prescribing corticosteroids to treat corticosteroid-responsive conditions in sickle cell disease (SCD) patients because their use can be associated with complications (increased hospital readmission, rebound pain, strokes, avascular necrosis, acute chest syndrome). Conseque...

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Detalles Bibliográficos
Autores principales: Almeida, Luis E. F., Damsker, Jesse M., Albani, Sarah, Afsar, Nina, Kamimura, Sayuri, Pratt, Drew, Kleiner, David E., Quezado, Martha, Gordish-Dressman, Heather, Quezado, Zenaide M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904156/
https://www.ncbi.nlm.nih.gov/pubmed/29666400
http://dx.doi.org/10.1038/s41598-018-24274-6