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Altered function and maturation of primary cortical neurons from a 22q11.2 deletion mouse model of schizophrenia

Given its high penetrance, clearly delineated and evolutionary conserved genomic structure, mouse models of the 22q11.2 deletion provide an ideal organism-based and cell-based model of this well-established disease mutation for schizophrenia. In this study we examined the development of changes in i...

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Detalles Bibliográficos
Autores principales: Sun, Ziyi, Williams, Damian J., Xu, Bin, Gogos, Joseph A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904157/
https://www.ncbi.nlm.nih.gov/pubmed/29666363
http://dx.doi.org/10.1038/s41398-018-0132-8