Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR

Aryl hydrocarbon receptor (AhR) is a nuclear receptor that controls xenobiotic detoxification via induction of cytochrome P450 1A1 (CYP1A1) and regulates immune responses in the intestine. Metabolites of L-tryptophan activate AhR, which confers protection against intestinal inflammation. We tested t...

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Detalles Bibliográficos
Autores principales: Manzella, Christopher, Singhal, Megha, Alrefai, Waddah A., Saksena, Seema, Dudeja, Pradeep K., Gill, Ravinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904159/
https://www.ncbi.nlm.nih.gov/pubmed/29666456
http://dx.doi.org/10.1038/s41598-018-24213-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904159/
https://www.ncbi.nlm.nih.gov/pubmed/29666456
http://dx.doi.org/10.1038/s41598-018-24213-5

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