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Serotonin is an endogenous regulator of intestinal CYP1A1 via AhR

Aryl hydrocarbon receptor (AhR) is a nuclear receptor that controls xenobiotic detoxification via induction of cytochrome P450 1A1 (CYP1A1) and regulates immune responses in the intestine. Metabolites of L-tryptophan activate AhR, which confers protection against intestinal inflammation. We tested t...

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Detalles Bibliográficos
Autores principales:	Manzella, Christopher, Singhal, Megha, Alrefai, Waddah A., Saksena, Seema, Dudeja, Pradeep K., Gill, Ravinder K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904159/ https://www.ncbi.nlm.nih.gov/pubmed/29666456 http://dx.doi.org/10.1038/s41598-018-24213-5

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