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Extensive T cell cross-reactivity between diverse seasonal influenza strains in the ferret model

Influenza virus causes widespread, yearly epidemics by accumulating surface protein mutations to escape neutralizing antibodies established from prior exposure. In contrast to antibody epitopes, T cell mediated immunity targets influenza epitopes that are more highly conserved and have potential for...

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Detalles Bibliográficos
Autores principales: Reber, Adrian J., Music, Nedzad, Kim, Jin Hyang, Gansebom, Shane, Chen, Jufu, York, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904180/
https://www.ncbi.nlm.nih.gov/pubmed/29666412
http://dx.doi.org/10.1038/s41598-018-24394-z