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Extensive T cell cross-reactivity between diverse seasonal influenza strains in the ferret model
Influenza virus causes widespread, yearly epidemics by accumulating surface protein mutations to escape neutralizing antibodies established from prior exposure. In contrast to antibody epitopes, T cell mediated immunity targets influenza epitopes that are more highly conserved and have potential for...
Autores principales: | Reber, Adrian J., Music, Nedzad, Kim, Jin Hyang, Gansebom, Shane, Chen, Jufu, York, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904180/ https://www.ncbi.nlm.nih.gov/pubmed/29666412 http://dx.doi.org/10.1038/s41598-018-24394-z |
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