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Classical NF-κB Metabolically Reprograms Sarcoma Cells Through Regulation of Hexokinase 2

BACKGROUND: Metabolic reprogramming has emerged as a cancer hallmark, and one of the well-known cancer-associated metabolic alterations is the increase in the rate of glycolysis. Recent reports have shown that both the classical and alternative signaling pathways of nuclear factor κB (NF-κB) play im...

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Detalles Bibliográficos
Autores principales: Londhe, Priya, Yu, Peter Y., Ijiri, Yuichi, Ladner, Katherine J., Fenger, Joelle M., London, Cheryl, Houghton, Peter J., Guttridge, Denis C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904193/
https://www.ncbi.nlm.nih.gov/pubmed/29696133
http://dx.doi.org/10.3389/fonc.2018.00104