Gα(i) Signaling Promotes Marginal Zone B Cell Development by Enabling Transitional B Cell ADAM10 Expression

The follicular (FO) versus marginal zone (MZ) B cell fate decision in the spleen depends upon BCR, BAFF, and Notch2 signaling. Whether or how G(i) signaling affects this fate decision is unknown. Here, we show that direct contact with Notch ligand expressing stromal cells (OP9-Delta-like 1) cannot p...

Descripción completa

Detalles Bibliográficos
Autores principales: Hwang, Il-Young, Boularan, Cedric, Harrison, Kathleen, Kehrl, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904254/
https://www.ncbi.nlm.nih.gov/pubmed/29696016
http://dx.doi.org/10.3389/fimmu.2018.00687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904254/
https://www.ncbi.nlm.nih.gov/pubmed/29696016
http://dx.doi.org/10.3389/fimmu.2018.00687

Ejemplares similares