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Can oliceridine (TRV130), an ideal novel µ receptor G protein pathway selective (µ-GPS) modulator, provide analgesia without opioid-related adverse reactions?

All drugs have both favorable therapeutic and untoward adverse effects. Conventional opioid analgesics possess both analgesia and adverse reactions, such as nausea, vomiting, and respiratory depression. The opioid ligand binds to µ opioid receptor and non-selectively activates two intracellular sign...

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Detalles Bibliográficos
Autores principales: Ok, Hwoe Gyeong, Kim, Su Young, Lee, Su Jung, Kim, Tae Kyun, Huh, Billy K, Kim, Kyung Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904350/
https://www.ncbi.nlm.nih.gov/pubmed/29686804
http://dx.doi.org/10.3344/kjp.2018.31.2.73