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Can oliceridine (TRV130), an ideal novel µ receptor G protein pathway selective (µ-GPS) modulator, provide analgesia without opioid-related adverse reactions?
All drugs have both favorable therapeutic and untoward adverse effects. Conventional opioid analgesics possess both analgesia and adverse reactions, such as nausea, vomiting, and respiratory depression. The opioid ligand binds to µ opioid receptor and non-selectively activates two intracellular sign...
Autores principales: | Ok, Hwoe Gyeong, Kim, Su Young, Lee, Su Jung, Kim, Tae Kyun, Huh, Billy K, Kim, Kyung Hoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Pain Society
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904350/ https://www.ncbi.nlm.nih.gov/pubmed/29686804 http://dx.doi.org/10.3344/kjp.2018.31.2.73 |
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