GLYX-13 Ameliorates Schizophrenia-Like Phenotype Induced by MK-801 in Mice: Role of Hippocampal NR2B and DISC1

Background: Evidence supports that the hypofunction of N-methyl-D-aspartate receptor (NMDAR) and downregulation of disrupted-in-schizophrenia 1 (DISC1) contribute to the pathophysiology of schizophrenia. N-Methyl D-aspartate receptor subtype 2B (NR2B)-containing NMDAR are associated with cognitive d...

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Detalles Bibliográficos
Autores principales: Zhou, Dongsheng, Lv, Dan, Wang, Zhen, Zhang, Yanhua, Chen, Zhongming, Wang, Chuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904356/
https://www.ncbi.nlm.nih.gov/pubmed/29695955
http://dx.doi.org/10.3389/fnmol.2018.00121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904356/
https://www.ncbi.nlm.nih.gov/pubmed/29695955
http://dx.doi.org/10.3389/fnmol.2018.00121

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