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Type II Secretion-Dependent Aminopeptidase LapA and Acyltransferase PlaC Are Redundant for Nutrient Acquisition during Legionella pneumophila Intracellular Infection of Amoebas

Legionella pneumophila genes encoding LapA, LapB, and PlaC were identified as the most highly upregulated type II secretion (T2S) genes during infection of Acanthamoeba castellanii, although these genes had been considered dispensable on the basis of the behavior of mutants lacking either lapA and l...

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Detalles Bibliográficos
Autores principales: White, Richard C., Gunderson, Felizza F., Tyson, Jessica Y., Richardson, Katherine H., Portlock, Theo J., Garnett, James A., Cianciotto, Nicholas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904407/
https://www.ncbi.nlm.nih.gov/pubmed/29666285
http://dx.doi.org/10.1128/mBio.00528-18