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Pathogenic Effects of IFIT2 and Interferon-β during Fatal Systemic Candida albicans Infection

A balanced immune response to infection is essential to prevent the pathology and tissue damage that can occur from an unregulated or hyperactive host defense. Interferons (IFNs) are critical mediators of the innate defense to infection, and in this study we evaluated the contribution of a specific...

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Detalles Bibliográficos
Autores principales: Stawowczyk, Marcin, Naseem, Shamoon, Montoya, Valeria, Baker, Darren P., Konopka, James, Reich, Nancy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904408/
https://www.ncbi.nlm.nih.gov/pubmed/29666281
http://dx.doi.org/10.1128/mBio.00365-18