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Human Immunodeficiency Virus Tat Protein Aids V Region Somatic Hypermutation in Human B Cells

Long-term survivors of human immunodeficiency virus (HIV) infection have been shown to have a greatly increased incidence of B cell lymphomas. This increased lymphomagenesis suggests some link between HIV infection and the destabilization of the host B cell genome, a phenomenon also suggested by the...

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Detalles Bibliográficos
Autores principales: Wang, Xiaohua, Duan, Zhi, Yu, Guojun, Fan, Manxia, Scharff, Matthew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904410/
https://www.ncbi.nlm.nih.gov/pubmed/29666292
http://dx.doi.org/10.1128/mBio.02315-17