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Allergic T(H)2 Response Governed by B-Cell Lymphoma 6 Function in Naturally Occurring Memory Phenotype CD4(+) T Cells

Transcriptional repressor B-cell lymphoma 6 (Bcl6) appears to regulate T(H)2 immune responses in allergies, but its precise role is unclear. We previously reported that Bcl6 suppressed IL-4 production in naïve CD4(+) T cell-derived memory T(H)2 cells. To investigate Bcl6 function in allergic respons...

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Detalles Bibliográficos
Autores principales: Ogasawara, Takashi, Kohashi, Yuko, Ikari, Jun, Taniguchi, Toshibumi, Tsuruoka, Nobuhide, Watanabe-Takano, Haruko, Fujimura, Lisa, Sakamoto, Akemi, Hatano, Masahiko, Hirata, Hirokuni, Fukushima, Yasutsugu, Fukuda, Takeshi, Kurasawa, Kazuhiro, Tatsumi, Koichiro, Tokuhisa, Takeshi, Arima, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904433/
https://www.ncbi.nlm.nih.gov/pubmed/29696026
http://dx.doi.org/10.3389/fimmu.2018.00750