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Quantifying the Evolutionary Conservation of Genes Encoding Multidrug Efflux Pumps in the ESKAPE Pathogens To Identify Antimicrobial Drug Targets

Increasing rates of antibiotic-resistant bacterial infection are one of the most pressing contemporary global health concerns. The ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species) have bee...

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Detalles Bibliográficos
Autores principales: Brooks, Lauren E., Ul-Hasan, Sabah, Chan, Benjamin K., Sistrom, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904435/
https://www.ncbi.nlm.nih.gov/pubmed/29719870
http://dx.doi.org/10.1128/mSystems.00024-18