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Stage 1 Registered Report: Variation in neurodevelopmental outcomes in children with sex chromosome trisomies: protocol for a test of the double hit hypothesis

Background: The presence of an extra sex chromosome is associated with an increased rate of neurodevelopmental difficulties involving language. Group averages, however, obscure a wide range of outcomes. Hypothesis: The 'double hit' hypothesis proposes that the adverse impact of the extra s...

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Detalles Bibliográficos
Autores principales: Newbury, Dianne F., Simpson, Nuala H., Thompson, Paul A., Bishop, Dorothy V. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904730/
https://www.ncbi.nlm.nih.gov/pubmed/29744390
http://dx.doi.org/10.12688/wellcomeopenres.13828.2