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Stemness-Attenuating miR-503-3p as a Paracrine Factor to Regulate Growth of Cancer Stem Cells

Cancer stem cells (CSCs) with self-renewal abilities endorse cellular heterogeneity, resulting in metastasis and recurrence. However, there are no promising therapeutics directed against CSCs. Herein, we found that miR-503-3p inhibited tumor growth via the regulation of CSC proliferation and self-re...

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Detalles Bibliográficos
Autores principales: Seo, Minkoo, Kim, Seung Min, Woo, Eun Young, Han, Ki-Cheol, Park, Eun Joo, Ko, Seongyeol, Choi, Eun wook, Jang, Mihue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904772/
https://www.ncbi.nlm.nih.gov/pubmed/29849663
http://dx.doi.org/10.1155/2018/4851949