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Prostaglandin E(2) Inhibits Prostate Cancer Progression by Countervailing Tumor Microenvironment-Induced Impairment of Dendritic Cell Migration through LXRα/CCR7 Pathway

Migration and homing of dendritic cells (DCs) to lymphoid organs are quite crucial for T cell-induced immune response against tumor. However, tumor microenvironment can make some tumor cells escape immune response by impairing DC migration. Prostaglandin E(2) (PGE(2)) plays important roles in initia...

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Detalles Bibliográficos
Autores principales: Youlin, Kuang, Weiyang, He, Simin, Liang, Xin, Gou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904800/
https://www.ncbi.nlm.nih.gov/pubmed/29850633
http://dx.doi.org/10.1155/2018/5808962