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Microsatellite instability in prostate cancer by PCR or next-generation sequencing

BACKGROUND: Microsatellite instability (MSI) is now being used as a sole biomarker to guide immunotherapy treatment for men with advanced prostate cancer. Yet current molecular diagnostic tests for MSI have not been evaluated for use in prostate cancer. METHODS: We evaluated two next-generation sequ...

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Detalles Bibliográficos
Autores principales: Hempelmann, Jennifer A., Lockwood, Christina M., Konnick, Eric Q., Schweizer, Michael T., Antonarakis, Emmanuel S., Lotan, Tamara L., Montgomery, Bruce, Nelson, Peter S., Klemfuss, Nola, Salipante, Stephen J., Pritchard, Colin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904988/
https://www.ncbi.nlm.nih.gov/pubmed/29665853
http://dx.doi.org/10.1186/s40425-018-0341-y