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Selective localization of IgG from cerebrospinal fluid to brain parenchyma

BACKGROUND: Encounter of autoantibodies with specific antigens can lead to hypersensitivity reactions and pathology. In multiple sclerosis and neuromyelitis optica spectrum disease (NMOSD), immunoglobulin-G (IgG) deposition has been observed in pathological lesions in the central nervous system. The...

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Detalles Bibliográficos
Autores principales: Mørch, Marlene Thorsen, Sørensen, Sofie Forsberg, Khorooshi, Reza, Asgari, Nasrin, Owens, Trevor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5904996/
https://www.ncbi.nlm.nih.gov/pubmed/29665816
http://dx.doi.org/10.1186/s12974-018-1159-8