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The CXCL5/CXCR2 axis contributes to the epithelial-mesenchymal transition of nasopharyngeal carcinoma cells by activating ERK/GSK-3β/snail signalling

BACKGROUND: Distant metastasis is the major cause of treatment failure in patients with nasopharyngeal carcinoma (NPC). Although several biomarkers correlate with metastasis and prognosis, the molecular mechanisms of NPC development and progression remain unclear. METHODS: Quantitative RT-PCR (qRT-P...

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Detalles Bibliográficos
Autores principales: Qiu, Wen-Ze, Zhang, Hai-Bo, Xia, Wei-Xiong, Ke, Liang-Ru, Yang, Jing, Yu, Ya-Hui, Liang, Hu, Huang, Xin-Jun, Liu, Guo-Ying, Li, Wang-Zhong, Xiang, Yan-Qun, Kang, Tie-Bang, Guo, Xiang, Lv, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905166/
https://www.ncbi.nlm.nih.gov/pubmed/29665837
http://dx.doi.org/10.1186/s13046-018-0722-6