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Synthesis and in vitro biochemical evaluation of oxime bond-linked daunorubicin–GnRH-III conjugates developed for targeted drug delivery

Gonadotropin releasing hormone-III (GnRH-III), a native isoform of the human GnRH isolated from sea lamprey, specifically binds to GnRH receptors on cancer cells enabling its application as targeting moieties for anticancer drugs. Recently, we reported on the identification of a novel daunorubicin–G...

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Detalles Bibliográficos
Autores principales: Schuster, Sabine, Biri-Kovács, Beáta, Szeder, Bálint, Farkas, Viktor, Buday, László, Szabó, Zsuzsanna, Halmos, Gábor, Mező, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905287/
https://www.ncbi.nlm.nih.gov/pubmed/29719573
http://dx.doi.org/10.3762/bjoc.14.64