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The nonmotor adaptor HMMR dampens Eg5-mediated forces to preserve the kinetics and integrity of chromosome segregation

Mitotic spindle assembly and organization require forces generated by motor proteins. The activity of these motors is regulated by nonmotor adaptor proteins. However, there are limited studies reporting the functional importance of adaptors on the balance of motor forces and the promotion of faithfu...

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Detalles Bibliográficos
Autores principales: Chen, Helen, Connell, Marisa, Mei, Lin, Reid, Gregor S. D., Maxwell, Christopher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905292/
https://www.ncbi.nlm.nih.gov/pubmed/29386294
http://dx.doi.org/10.1091/mbc.E17-08-0531